The EFRE-projects are funded by the European Union and the State of North Rhine-Westphalia. Further information can be found at www.efre.nrw.de or at www.wirtschaft.nrw.de.
In order to be able to treat vascular bulges in the brain better (so called cerebral aneurysms) in order to avoid strokes, an new intraaneurysmal implant with flow-modulation properties is going to be developed. The use of an innovative combination of materials should ensure simplified implantation and ideal sealing of the aneurysm. The challanges that need to be solved are to develop the construction of the filigree nitinol support structure as well as the research and development of a functionalized, fiber-reinforced membrane to redirect the blood flow.
In order to be able to further improve the treatment of vascular malformations with implants such as stents, occlusion spirals or flow diverters, even in very small an branched vessels of the brain, new approaches to implant insertion are required. For this purpose a technology and material platform should be developed to fix the implant again so that it can be detached from the delivery instrument. After a successful development of the necessary material combinations a preclinical evaluation based on an application development of a specific implant is planned.
The aim is to develop a hybrid roll for cold rolling applications that is based on a completely new combination of materials and processes. This can replace the hard-chronium-plated cold rolls currently used worldwide, produced by melt metallurgy. The very negative environmental and health effects caused by the chromium-(VI) released during hard chrome plating are going to be avoided. At the same time, the wear resistance of the roll is significantly increased, so that improved economic efficiency is also achieved wen rolling high-strength products for lightweight construction applications.